Drug intelligence / Profile preview

CN-105

Development stage
Phase 2
Lead developer
AegisCN
Modality
Small Molecules, Peptides
Administration
Intravenous
01

Overview

CN-105 is a neuroprotective pentapeptide with the sequence Acetyl-Valine-Serine-Arginine-Arginine-Arginine-NH2. It acts as an apolipoprotein E (apoE) mimetic, targeting neuroinflammatory pathways. CN-105 is being developed for the treatment of cerebral hemorrhage, cognition disorders, and delirium. It is classified as a neuropeptide and neuroprotectant.

Other names
Ac-VSRRR-NH2Ac-VSRRR-NH-2Ac-VSRRR-NH 2N-Acetyl-L-valyl-L-seryl-L-arginyl-L-arginyl-L-argininamide
02

Targets

LRP1 (Prolow-density lipoprotein receptor-related protein 1)

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