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CNC-301
- Development stage
- Preclinical
- Lead developer
- CNcure
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Intravenous
01
Overview
CNC-301 is an early-stage microbiome-based therapeutic candidate developed by CNcure for the treatment of colon cancer. Utilizing CNcure's microbiome platform, CNC-301 is designed as a live biotherapeutic product (LBP) that modulates the gut microbiota to exert anti-tumor effects. The program is currently in the hit-to-lead phase, focusing on identifying and optimizing bacterial strains that can effectively alter the tumor microenvironment or stimulate systemic anti-cancer immune responses.
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