Cnidium monnieri fruit

Cnidium monnieri fruit is the dried fruit of the plant *Cnidium monnieri* (L.) Cusson from the Apiaceae family. It is a traditional herbal medicine widely used in China, Japan, Korea, and Vietnam under various names such as She chuang zi (Chinese), Jashoshi (Japanese), Sasangia (Korean), and Xa sang tu (Vietnamese). The main active constituents are coumarins—especially osthole—which have been shown to possess a broad range of pharmacological properties including antipruritic, anti-allergic, antidermatophytic, antibacterial, antifungal, anti-osteoporotic effects as well as pro-erectile activity. Osthole has demonstrated inhibition of urate transporter 1 (URAT1) *in vitro* and may contribute to potential benefits for hyperuricemia or gout. The precise molecular mechanisms remain incompletely understood but may involve pathways similar to those targeted by phosphodiesterase inhibitors in erectile tissue.

Other names

Cnidii FructusCnidium seedShe chuang ziJashoshiSasangiaXa sang tu