Drug intelligence / Profile preview

CNP-Arg-PTX

Development stage
Preclinical
Lead developer
SiNON Nano Sciences
Modality
Nanoparticles → Drug Delivery Systems, Small Molecules
01

Overview

**CNP-Arg-PTX** is a preclinical paclitaxel nanomedicine developed by SiNON Nano Sciences for cancer, including brain-directed oncology applications. It encapsulates **paclitaxel** in a carbon nanoparticle carrier functionalized with arginine, with the delivery system intended to improve transport across the blood-brain barrier, tumor-directed delivery, drug stability, and controlled release. The therapeutic cytotoxic activity is expected to derive from paclitaxel-mediated stabilization of microtubules and disruption of mitosis.

02

Targets

TUBB (Tubulin (alpha and beta subunits))

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