Drug intelligence / Profile preview

CNP-Arg-TPT

Development stage: Preclinical
Lead developer: SiNON Nano Sciences
Modality: Nanoparticles → Drug Delivery Systems, Small Molecules

Overview

**CNP-Arg-TPT** is a preclinical, arginine-functionalized carbon nanoparticle formulation that encapsulates the topoisomerase I inhibitor topotecan. SiNON Nano Sciences is developing the formulation to enhance blood-brain barrier penetration, brain-localized drug delivery, and sustained release of topotecan for cancer, including brain tumors. ([sinontx.com](https://sinontx.com/product/cnp-arg-tpt/))

Targets

TOP1 (DNA Topoisomerase I)

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