Drug intelligence / Profile preview

CNTO 0007

Development stage
Phase 1
Lead developer
Janssen Research & Development
Modality
Stem Cell Therapies → Cell Therapies
Administration
Intravenous
01

Overview

CNTO 0007 is an investigational intravenously administered cell therapy developed by Janssen Research & Development (a Johnson & Johnson company) for neuroprotection and cell replacement. It is a stem cell therapy containing human umbilical tissue-derived cells (hUTC), designed to promote recovery after ischemic cerebral infarction (stroke). The drug was evaluated in Phase 1 clinical trials for its safety and tolerability in patients who had experienced ischemic stroke, but no further development has been reported since then. Its mechanism of action involves replacing damaged or lost neural cells to support functional recovery following neurological injury.

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