Drug intelligence / Profile preview

Co-Mekina

Development stage
Unknown
Lead developer
Daewoong Pharmaceutical
Modality
Small Molecules
Administration
Intranasal
01

Overview

Co-Mekina is a combination intranasal spray developed and marketed by Daewoong Pharmaceutical for the symptomatic relief of acute rhinitis and allergic rhinitis. The formulation typically contains xylometazoline hydrochloride, a sympathomimetic agent that acts as an alpha-adrenergic agonist to induce vasoconstriction in the nasal mucosa, and chlorpheniramine maleate, a first-generation antihistamine that antagonizes H1 receptors. By combining these two active ingredients, the spray provides rapid relief from nasal congestion, sneezing, and rhinorrhea associated with the common cold or hay fever. It is positioned as a fast-acting over-the-counter (OTC) treatment for upper respiratory symptoms.

Brand names
Co-MekinaCO-MEKINA Spray
Other names
Co-Mekina Nasal Spray
02

Targets

ADRA1A (α1A)ADRA2A (α2A)HRH1 (Histamine H1 Receptor)

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