Drug intelligence / Profile preview

coal tar + salicylic acid (Percos)

Development stage
Unknown
Lead developer
Percos
Modality
Small Molecules
Administration
Topical
01

Overview

Protar is a topical combination of coal tar and salicylic acid used to treat chronic, scaly skin and scalp conditions such as psoriasis, seborrheic dermatitis, and severe dandruff. Coal tar acts as a keratoplastic agent, slowing down the rapid proliferation of skin cells and reducing scaling, redness, and inflammation. Salicylic acid serves as a keratolytic agent, softening and dissolving thick, scaly patches of skin to facilitate exfoliation and enhance skin texture. Together, these active ingredients promote smoother skin and support the skin's natural repair process.

Brand names
Protar
Other names
coal tar and salicylic acidcoal tar/salicylic acid
02

Targets

AHR (Aryl hydrocarbon receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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