Drug intelligence / Profile preview

cobalamin

Development stage
Unknown
Lead developer
Núcleo de Pesquisa e Desenvolvimento de Medicamentos da Universidade Federal do Ceará
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

Cobalamin, commonly known as Vitamin B12, is a water-soluble vitamin being investigated as an adjuvant therapy for drug-induced movement disorders by the Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara. The drug is specifically being evaluated for its ability to treat syndromes such as tardive dyskinesia, dystonia, and parkinsonism in patients receiving antipsychotic medications for schizophrenia, schizoaffective disorder, or bipolar disorder. The therapeutic rationale is based on cobalamin's antioxidant properties, which may counteract the oxidative stress and free radical generation resulting from dopamine metabolism and chronic D2 receptor blockade in the striatum. In clinical trials, it is administered as an oral tablet at a dosage of 2mg daily.

Brand names
B-12 Compliance KitB12 Compliance KitB 12 Compliance KitB-12 Injection KitB12 Injection KitB 12 Injection KitCyominDodexLA-12LA12LA 12Nutri-TwelvePhysicians EZ Use B-12PrimabaltVitamin Deficiency Injectable System - B12
Other names
Vitamin B12cyanocobalaminmethylcobalaminadenosylcobalaminhydroxocobalamin
02

Targets

MMUT (Methylmalonyl-coenzyme A mutase)MTR (Methionine synthase)

Beyond the preview

Go deeper on cobalamin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on cobalamin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call