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cobratide
- Development stage
- Unknown
- Modality
- Peptides
- Administration
- Oral, Rectal
01
Overview
Cobratide is a neurotoxin peptide derived from the venom of the Chinese cobra. It is used to treat chronic pains such as late-stage cancer pain, chronic joint pain, sciatica, and trigeminal neuralgia. Cobratide acts as a postsynaptic neurotoxin, binding to acetylcholine receptors at neuromuscular junctions, thereby blocking nerve signal transmission and providing analgesic effects without habituation or tolerance[1][2].
- Other names
- 科博肽
02
Targets
GABRR (GABA-A receptor subunit rho)CHRNA7 (α7 nicotinic receptor)Muscle-type nicotinic acetylcholine receptor
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