COC183B2-800

COC183B2-800 is a fluorescent probe composed of the monoclonal antibody COC183B2 conjugated to the near-infrared dye IRDye800CW, developed for the specific targeting and intraoperative visualization of epithelial ovarian cancer (EOC) lesions. The antibody recognizes the OC183B2 antigen, which is highly expressed in EOC tissues, enabling selective tumor imaging for fluorescence-guided surgery. The probe demonstrates high tumor specificity and a favorable tumor-to-background signal ratio in animal models and is primarily metabolized through the liver. COC183B2-800 represents an investigational molecular imaging agent with potential use as a diagnostic and surgical adjunct in ovarian cancer patients[1][5][9].

Other names

IRDye800CW-conjugated COC183B2IRDye-800CW-conjugated COC183B2IRDye 800CW-conjugated COC183B2