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Coccidioides immitis spherule
- Development stage
- Approved
- Lead developer
- Nielsen BioSciences
- Modality
- Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intradermal
01
Overview
Coccidioides immitis spherule is a biologic diagnostic agent used as a skin test antigen to detect delayed-type hypersensitivity to Coccidioides immitis, the fungus responsible for coccidioidomycosis (Valley fever). It is indicated for use in adults aged 18–64 with a history of pulmonary coccidioidomycosis. The test involves intradermal administration; a positive result is defined by an induration greater than 5 mm at the injection site after 48 hours. This product does not treat or prevent infection but helps identify prior exposure or immune response to the pathogen[1][7][9].
- Brand names
- Spherusol
- Other names
- Coccidioides immitis spherule-derived skin test antigen
02
Targets
γδ TCR (T-cell receptor)
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