Drug intelligence / Profile preview

coccinia cordifolia extract

Development stage
Unknown
Lead developer
St. John's Research Institute
Administration
Oral
01

Overview

Coccinia cordifolia extract, derived from the perennial climber belonging to the Cucurbitaceae family (also known as *Coccinia indica* or Ivy gourd), is a herbal supplement traditionally used in Ayurvedic medicine for its hypoglycemic properties. The extract, typically obtained from the leaves or fruit, is primarily investigated for the management of newly diagnosed Type 2 diabetes mellitus as an adjunct to lifestyle interventions. It is believed to improve glucose tolerance and lower blood glucose levels through mechanisms such as the inhibition of glucose-6-phosphatase and alpha-glucosidase, as well as potential insulin-mimetic effects. Clinical research has focused on its efficacy in reducing fasting and postprandial blood glucose in patients requiring non-pharmacological glycemic control.

Other names
Coccinia indica extractIvy gourd extractCoccinia grandis extractKovai fruit extract
02

Targets

G6PC1 (Glucose 6-phosphatase alpha)Sucrase-Isomaltase

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