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Coccinia cordifolia extract, derived from the perennial climber belonging to the Cucurbitaceae family (also known as *Coccinia indica* or Ivy gourd), is a herbal supplement traditionally used in Ayurvedic medicine for its hypoglycemic properties. The extract, typically obtained from the leaves or fruit, is primarily investigated for the management of newly diagnosed Type 2 diabetes mellitus as an adjunct to lifestyle interventions. It is believed to improve glucose tolerance and lower blood glucose levels through mechanisms such as the inhibition of glucose-6-phosphatase and alpha-glucosidase, as well as potential insulin-mimetic effects. Clinical research has focused on its efficacy in reducing fasting and postprandial blood glucose in patients requiring non-pharmacological glycemic control.
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