cod allergenic extract

Cod, unspecified is an allergenic extract derived from cod fish (typically Gadus species) used as a diagnostic tool to identify IgE-mediated hypersensitivity in patients suspected of having a cod fish allergy. The extract contains a complex mixture of proteins, most notably the calcium-binding muscle protein parvalbumin (Gad c 1), which is the primary allergen. When applied during skin prick testing or administered intradermally, the proteins in the extract cross-link allergen-specific IgE antibodies bound to the surface of mast cells and basophils. This interaction triggers the degranulation of these cells and the subsequent release of inflammatory mediators like histamine, resulting in a visible wheal-and-flare reaction that confirms sensitization.

Other names

Cod, unspecifiedCod fish allergenic extractCodfish extractAllergenic extract, Cod