Drug intelligence / Profile preview

codeine

Development stage
Approved
Modality
Small Molecules
Administration
Oral, Intramuscular, Subcutaneous, Rectal
01

Overview

Codeine is an opioid medication used for the short-term relief of mild to moderate pain and as a cough suppressant. It functions as a prodrug, being converted into morphine in the body, which acts as a selective agonist of the μ-opioid receptor (MOR). Codeine is available in various forms, including tablets and syrups, often combined with other medications like acetaminophen or chlorpheniramine.

Brand names
ActacodeCodateCodinfosCodelixCodicept
Other names
(−)-Codeine(5α,6α)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-olCodeinCodeínaCodéineCodeine anhydrousCodeine polistirexCodeinumL-CodeineMethylmorphineMorphine 3-methyl etherMorphine3-methyl etherMorphine-3-methyl etherMorphine monomethyl etherO3-MethylmorphineO-3-MethylmorphineO 3-Methylmorphine
02

Targets

KOR (Kappa opioid receptor)MOR (Mu opioid receptor)DOR (Opioid Receptor Delta 1)

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