Drug intelligence / Profile preview

COFBRO

Development stage
Unknown
Lead developer
Wellmed Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

COFBRO is a combination respiratory medication developed and marketed by Wellmed Pharma. It contains four active ingredients: terbutaline sulphate, a beta-2 adrenergic receptor agonist that acts as a bronchodilator; ambroxol hydrochloride, a mucolytic agent that thins mucus; guaiphenesin, an expectorant that increases the volume of airway secretions to facilitate their removal; and menthol, which provides a soothing effect. This formulation is designed as a small molecule combination therapy for treating respiratory conditions involving bronchospasm and mucus congestion, such as asthma, chronic obstructive pulmonary disease (COPD), and other respiratory tract disorders. It is typically administered as an oral syrup.

Brand names
COFBRO
02

Targets

ADRB2 (β2)TRPM8 (Transient receptor potential cation channel subfamily M member 8)

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