Drug intelligence / Profile preview

coicis semen

Development stage
Unknown
Modality
Small Molecules
Administration
Oral (as Decoction/tea), Oral (as Food Ingredient)
01

Overview

Coicis semen is the dried mature seed of *Coix lacryma-jobi* L. var. mayuen (Roman.) Stapf (family Gramineae), commonly known as coix seed or Job’s tears. In Traditional Chinese Medicine (TCM), it is classified as a herb that relieves dampness and is used to promote diuresis, strengthen the spleen, stop diarrhea, clear heat and expel pus. It is considered sweet and bland in flavor with a slightly cold nature and primarily acts on the spleen, stomach, and lung meridians[3][4][2]. Pharmacologically, it has demonstrated anti-inflammatory effects and may modulate fluid redistribution in the body[3]. The main active components include polysaccharides and oils such as coixenolide; however its precise mechanism of action at a molecular level remains unclear in Western pharmacology.

Brand names
KanglaiteKLT
Other names
yi yi rencoix seedjob's tearsadlaysheng yi mi薏苡仁生薏苡仁
02

Targets

CASP3 (Caspase-3)

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