Drug intelligence / Profile preview

coix seed polysaccharide

Development stage
Preclinical
Administration
Oral, Systemic
01

Overview

Coix seed polysaccharide is a natural polysaccharide derived from Coix seed, a traditional Chinese medicine. It has been investigated for its anti-aging, antioxidant, immunomodulatory, and prebiotic properties. Structurally, it primarily consists of glucose linked by glycosidic bonds, with varying molecular weights depending on the purified form. It has shown potential in extending lifespan, reducing oxidative stress, suppressing senescence, and mitigating DNA damage. Furthermore, it can modulate gut microbiota, enhance beneficial metabolites, and act as an anticancer component, particularly when delivered via targeted microemulsions for hepatic tumors. Its applications are being explored in anti-aging therapies, prebiotic products, and as a dietary supplement for conditions like ulcerative colitis.

Other names
Coix seed polysaccharideCSP谷参
02

Targets

HCAR2 (Hydroxycarboxylic acid receptor 2)

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