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**Colaren** is a named dietary supplement product evaluated with annual intravenous zoledronic acid in a University of Guadalajara-sponsored Phase 3 study of secondary osteoporosis in HIV-positive and HIV-negative men. Public trial materials identify Colaren as a supplement but do not disclose its active ingredient composition, dosage form, manufacturer, or a defined molecular mechanism. It should therefore not be conflated with zoledronic acid, calcium, vitamin D, or any specific collagen product.
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