Drug intelligence / Profile preview

Colastar

Development stage
Unknown
Lead developer
Healthon Life Sciences
Modality
Small Molecules
Administration
Oral
01

Overview

Colastar (also referred to as Collastar) is a multi-ingredient nutraceutical product line developed and marketed by Healthon Lifesciences. It is designed for the management of joint and musculoskeletal conditions, such as osteoarthritis and inflammatory joint disorders. The formulation typically includes a combination of natural anti-inflammatory agents and joint-supportive compounds, including Boswellia serrata extract (standardized for 3-O-acetyl-11-keto-beta-boswellic acid or AKBA), chondroitin sulfate, bromelain, and curcuminoids. These ingredients work synergistically to inhibit pro-inflammatory enzymes like 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2), and to reduce the levels of inflammatory cytokines such as TNF-alpha and IL-1beta. The product is available in various formulations, including tablets and sachets, and is marketed as a branded generic in India.

Brand names
ColastarCollastarColastar PlusColastar ECCollastar PlusCollastar EC
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL1B (Interleukin-1 beta)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX12 (Arachidonate 12-lipoxygenase, 12S type)

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