Drug intelligence / Profile preview

cold compress gel

Development stage
Unknown
Lead developer
My Import
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Cold compress gel is a topical product designed for external application to provide localized cooling and pain relief. It typically contains menthol as the active ingredient (commonly at 2%), which acts as a counterirritant by stimulating nerves that sense pain or irritation, producing a cooling sensation that helps relieve minor muscle and joint pain[1][9]. The base of the gel often includes water and polymers such as sodium polyacrylate to retain coldness for extended periods[4]. Cold compress gels are used for temporary relief of aches associated with sprains, strains, bruises, arthritis, back pain, tendonitis, bursitis, sunburns, insect bites or stings, and other minor injuries. They are commonly used in first aid kits and physical therapy settings to reduce swelling (edema), inflammation, muscle spasms, and promote faster recovery after acute injuries[1][8][10]. The mechanism of action is primarily through vasoconstriction (narrowing blood vessels), numbing the area to reduce pain perception and limiting local inflammation.

Brand names
CHOICE PERSONAL CARE THERAPUTIC BLUE ICEAD SURGICAL Reusable Cold Gel Packs
Other names
cold gel packice gelcold therapy gel
02

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)

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