Drug intelligence / Profile preview

Coldangin

Development stage
Unknown
Lead developer
Sigmapharm Arzneimittel
Modality
Small Molecules
Administration
Oral
01

Overview

Coldangin is an over-the-counter antiseptic throat lozenge developed by Sigmapharm Arzneimittel. It is formulated as a fixed-dose combination of two active ingredients: 2,4-dichlorobenzyl alcohol (1.5 mg) and amylmetacresol (0.8 mg). Coldangin is indicated for the local treatment of acute inflammatory and catarrhal diseases of the mouth and throat, such as pharyngitis, laryngitis, gingivitis, tonsillitis, and sore throat. The active components act as local antiseptics with broad-spectrum antibacterial, antifungal, and antiviral properties. Additionally, they exert a mild local anesthetic effect by blocking voltage-gated sodium channels, providing rapid relief from throat pain and irritation.

Brand names
Coldangin
Other names
2,4-dichlorobenzyl alcohol + 6-n-amyl-m-cresol2,4-dichlorobenzyl alcohol + amylmetacresolamylmetacresol + 2,4-dichlorobenzyl alcoholamylmetacresol + dichlorobenzyl alcoholdichlorobenzyl alcohol + amylmetacresol
02

Targets

SCN2A (Voltage-gated sodium channel protein type 2 subunit alpha)

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