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Devaron is a brand name for colecalciferol (vitamin D3), a secosteroid that acts as a vitamin D receptor (VDR) agonist. It is an orally administered dietary supplement and medication used to regulate calcium and phosphorus homeostasis. In clinical research, specifically a trial conducted by the VU University Medical Centre in the Netherlands, Devaron was investigated for its potential to prevent depressive symptoms and improve physical functioning in adults aged 60 years and older. Colecalciferol is a prohormone that is metabolized in the liver to calcifediol and subsequently in the kidneys to its active form, calcitriol, which exerts pleiotropic effects on musculoskeletal and neurological health.
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