Drug intelligence / Profile preview

colecalciferol

Development stage
Unknown
Lead developer
Vrije University Medical Center
Modality
Small Molecules
Administration
Oral
01

Overview

Devaron is a brand name for colecalciferol (vitamin D3), a secosteroid that acts as a vitamin D receptor (VDR) agonist. It is an orally administered dietary supplement and medication used to regulate calcium and phosphorus homeostasis. In clinical research, specifically a trial conducted by the VU University Medical Centre in the Netherlands, Devaron was investigated for its potential to prevent depressive symptoms and improve physical functioning in adults aged 60 years and older. Colecalciferol is a prohormone that is metabolized in the liver to calcifediol and subsequently in the kidneys to its active form, calcitriol, which exerts pleiotropic effects on musculoskeletal and neurological health.

Brand names
Devaron
Other names
vitamin D3cholecalciferol
02

Targets

VDR (Vitamin D receptor)

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