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Colgate fluoride-free herbal toothpaste
- Development stage
- Unknown
- Lead developer
- Colgate-Palmolive
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Colgate fluoride-free herbal toothpaste is a dental care formulation developed by Colgate Palmolive, specifically designed for the prevention of dental cavities and the treatment of enamel demineralization. Unlike traditional dentifrices that rely on fluoride (such as sodium fluoride or monofluorophosphate), this product utilizes a chalk base (calcium carbonate) combined with herbal ingredients. The mechanism of action focuses on the tooth enamel surface, where the formulation aims to inhibit demineralization and promote remineralization by providing a calcium-rich environment and leveraging the therapeutic properties of its herbal components. It has been evaluated in Phase III, randomized, triple-blind, crossover clinical trials using intra-oral enamel models to compare its anti-cavity efficacy against standard fluoride toothpastes.
- Other names
- Fluoride free toothpaste in a chalk baseFluoride-free herbal toothpasteColgate herbal toothpaste
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