Drug intelligence / Profile preview

Colgate Maximum Cavity Protection

Development stage
Phase 2
Lead developer
Colgate-Palmolive
Modality
Small Molecules
Administration
Topical
01

Overview

**Colgate Maximum Cavity Protection** is an over-the-counter anticaries fluoride toothpaste developed and manufactured by Colgate-Palmolive. In the United States product presentation associated with the clinical-trial context, the active anticaries ingredient is **sodium monofluorophosphate 0.76%**, equivalent to 0.15% fluoride ion. During brushing, fluoride promotes remineralization of early enamel mineral loss and increases enamel resistance to acid-mediated demineralization, helping prevent dental caries. The name is also used internationally for related toothpaste products whose fluoride systems and excipient compositions may differ by market; this annotation reflects the sodium-monofluorophosphate Colgate Cavity Protection formulation associated with the provided trial context.

Brand names
Colgate Maximum Cavity ProtectionColgate Cavity Protection
Other names
Colgate Cavity Protection Toothpaste with FluorideColgate Cavity Protection Toothpaste
02

Targets

ENO (Alpha-enolase)HydroxyapatiteF-ATPase (Bacterial H+-translocating F1F0-ATPase)

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