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Colibiogen
- Development stage
- Phase 3
- Lead developer
- Laves-Arzneimittel
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Small Molecules, Peptides
- Administration
- Oral
01
Overview
Colibiogen is a naturopathic pharmaceutical product developed by Laves-Arzneimittel GmbH, primarily used for the treatment of intestinal disorders and the support of the immune system. It consists of a cell-free fermentation filtrate derived from the *Escherichia coli* strain Laves 1931 (L1931). This filtrate contains metabolic products such as glycolipids, peptides, fatty acids, and amino acids, along with biotin. It is marketed as a food for special medical purposes (FSMP) for the dietary management of irritable bowel syndrome (IBS) and is also used for inflammatory bowel diseases like Crohn's disease and colitis, as well as for post-antibiotic or post-chemotherapy rehabilitation. The product exerts anti-inflammatory and immunoregulatory effects on the intestinal mucosa, helping to restore the balance of the gut-associated lymphoid tissue (GALT).
- Brand names
- ColibiogenColibiogen oralColibiogen KinderColibiogen Laves
- Other names
- Escherichia coli strain Laves 1931 lysateE. coli L1931 fermentation filtrate
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