Drug intelligence / Profile preview

collagen

Development stage
Unknown
Lead developer
Viscofan
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Oral, Implant, Percutaneous
01

Overview

Collagen is the most abundant protein in the human body, serving as a primary structural component of connective tissues such as skin, bones, tendons, and cartilage. [6] Due to its versatile properties, collagen is utilized across various applications, including as a dietary supplement, a medical device component, and in cosmetic procedures. As a dietary supplement, it is often taken to support joint and skin health by providing the amino acid building blocks for the body's own collagen synthesis. [8, 16] A specific formulation of technologically modified bovine collagen, Satiscoll®, has been studied for weight management; this formulation has low digestibility and high water-swelling capacity, which induces a feeling of fullness when ingested, thereby reducing hunger and aiding in weight loss. [10, 14, 17] In medical and cosmetic applications, collagen is used as an injectable dermal filler (e.g., Bellafill, Sunmax) to correct wrinkles and scars by providing volume and as a bulking agent for vocal fold augmentation to treat voice disorders like hypophonia. [2, 3, 15] Collagen can be derived from various sources, including bovine, porcine, and marine life, and can be processed into different forms, such as native collagen, gelatin, or hydrolyzed collagen peptides. [8, 9]

Brand names
SunmaxNaticolSatiscollZydermZyplastPhonagelArtecollBellafillCosmodermCosmoplastColladewArcv PlusProluma RH Collagen
Other names
collagen peptideshydrolyzed collagen
02

Targets

ITGA2/ITGB1 (Integrin alpha-2/beta-1 receptor)DCN (Decorin)

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