Drug intelligence / Profile preview

collagen ii peptide

Development stage
Unknown
Lead developer
Hofseth BioCare
Modality
Peptides, Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Collagen II peptide refers to peptides derived from Type II collagen, a major structural component of cartilage. These peptides are often used as dietary supplements to support joint health. One example, undenatured type II collagen, is derived from marine sources like enzymatically processed salmon cartilage and bone. It is being investigated for its potential to reduce activity-related knee discomfort and improve functional performance in healthy adults. It is typically administered as a once-daily oral supplement. Its proposed mechanism involves inducing oral tolerance to collagen, thereby modulating the immune response related to joint health.

Brand names
NT-II™
Other names
Undenatured Type II CollagenSalmon Undenatured Type II Collagen
02

Targets

HLA-DRB1 (Human leukocyte antigen DR beta chain)TCR-Col2-DRB1*04:01 (T-cell receptor recognizing Type II Collagen/HLA-DRB1*04:01 complex)

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