Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
collagenase clostridium histolyticum-aaes + tranexamic acid
- Development stage
- Unknown
- Lead developer
- Endo International
- Modality
- Recombinant Proteins and Enzymes, Small Molecules
- Administration
- Subcutaneous, Oral
01
Overview
**Collagenase clostridium histolyticum-aaes + tranexamic acid** is a combination of an injectable enzymatic biologic (collagenase clostridium histolyticum-aaes, marketed as Qwo) and tranexamic acid, an antifibrinolytic small molecule, used off-label with the goal of reducing post-injection bruising in cosmetic treatment of moderate-to-severe cellulite in adult women. Collagenase clostridium histolyticum-aaes selectively degrades types I and III collagen in fibrous septa responsible for the dimpling appearance of cellulite, while tranexamic acid works by inhibiting plasminogen activation and reducing fibrinolysis and extravasation of blood, theoretically limiting bruising after subcutaneous intervention[3][4].
- Other names
- collagenase clostridium histolyticum-aaes + tranexamic acid
02
Targets
COL1 (Collagen type I)PLG (Plasminogen)
Beyond the preview
Go deeper on collagenase clostridium histolyticum-aaes + tranexamic acid.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on collagenase clostridium histolyticum-aaes + tranexamic acid.