Drug intelligence / Profile preview

colloidal bismuth pectin

Development stage
Phase 4
Lead developer
Shanxi Xinbaoyuan Pharmaceutical
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Administration
Oral
01

Overview

Colloidal bismuth pectin is an orally administered gastric mucosal protectant consisting of a compositionally non-stoichiometric complex of pectin and bismuth. In the acidic stomach environment, it forms a viscous colloidal layer that adheres preferentially to injured or inflamed gastric mucosa, helping shield the surface from acid and pepsin and supporting mucus secretion and mucosal repair. It also has local anti-Helicobacter pylori activity and is used in bismuth-containing eradication regimens with acid suppression and antibiotics. The substance is minimally systemically absorbed; formulations are used for chronic gastritis, peptic-ulcer disease, and related upper-gastrointestinal symptoms. ([ypk.39.net](https://ypk.39.net/861396/manual/))

Brand names
U比乐
Other names
胶体果胶铋pectin bismuthcolloidal pectin bismuth
02

Targets

PEP (Pepsin)

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