Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
colloidal gold-bound tumor necrosis factor
- Development stage
- Phase 1
- Lead developer
- Zahav Bioscience
- Modality
- Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
Colloidal gold-bound tumor necrosis factor is a nanoparticle delivery system consisting of recombinant human tumor necrosis factor (TNF) bound to pegylated colloidal gold nanoparticles. This drug formulation is designed to target TNF directly to tumor sites while reducing systemic toxicity. The drug is constructed by simultaneously binding recombinant human TNF and thiolyated polyethylene glycol to the surface of 27 nm colloidal gold particles, making the nanoparticles "invisible" to immune detection and enabling targeted delivery to tumor sites.
- Brand names
- AurasolMesoGold
- Other names
- colloidal gold-bound TNFColloidal Gold-Bound Recombinant Human Tumor Necrosis FactorTNF-bound colloidal gold
02
Targets
TNFRSF1A (Tumor necrosis factor receptor superfamily member 1A)TNFR2 (Tumor necrosis factor receptor superfamily member 1B)
Beyond the preview
Go deeper on colloidal gold-bound tumor necrosis factor.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on colloidal gold-bound tumor necrosis factor.