Drug intelligence / Profile preview

colloidal sulfur

Development stage
Phase 4
Lead developer
Vertellus
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Colloidal sulfur is a finely dispersed form of elemental sulfur (S) with a molecular weight of 32.07. It is widely used in cosmetics and dermatological products for its antimicrobial, anti-inflammatory, keratolytic (exfoliating), and sebum-regulating properties[1][2][3][4][6]. In skincare formulations—especially those targeting acne—it helps clear excess keratin and sebum from pores, inhibits the growth of bacteria and fungi on the skin surface, reduces inflammation associated with acne lesions, and promotes healing of damaged skin barriers[3][4][5]. Colloidal sulfur is generally considered milder than traditional precipitated or sublimed sulfur due to its smaller particle size and encapsulation technologies (e.g., microencapsulation with acacia gum or collagen), which improve stability and reduce irritation[3][6]. It is not systemically absorbed when used topically.

Brand names
羽素胶态硫
Other names
胶态硫colloidal sulphurINCI COLLOIDAL SULFURCAS 7704-34-9CAS7704-34-9CAS-7704-34-9
02

Targets

KRT (Keratin, type I cuticular Ha7)

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