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**Collpure** is an oral fixed-dose combination tablet marketed by Parnasa Mediworld for osteoarthritis and joint-health management. It contains diacerein, glucosamine sulfate, and methylsulfonylmethane. Diacerein is used to modulate interleukin-1-mediated inflammatory and cartilage-catabolic signaling, while glucosamine sulfate is intended to support cartilage matrix and proteoglycan synthesis; methylsulfonylmethane is a sulfur-containing adjunct used for its proposed anti-inflammatory and analgesic effects. The marketed tablet composition reported for Collpure is diacerein 50 mg, glucosamine 750 mg, and methylsulfonylmethane 250 mg. ([1mg.com](https://www.1mg.com/drugs/collpure-tablet-341320))
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