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Drug intelligence / Profile preview
combined herbal capsule
- Development stage
- Phase 3
- Lead developer
- Salamat Gostar Artiman Pharmaceutical
- Administration
- Oral
01
Overview
The combined herbal capsule (CHC) is a nutritional supplement composed of a mixture of powdered herbal products, including Cinnamomum, Berberis vulgaris fruit, Galega officinalis leaves, Vaccinium bracteatum thumb leaves, and Trigonella foenum-graecum seeds. It is designed to improve glycemic indices (fasting blood sugar, two hours postprandial blood sugar, and glycosylated hemoglobin) and lipid profiles (triglycerides, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) in patients with Type 2 Diabetes Mellitus (T2DM) and associated dyslipidemia. The individual components contribute to its anti-diabetic and anti-lipidemic effects through various mechanisms, such as regulating blood glucose, improving insulin sensitivity, and modulating lipid metabolism.
- Other names
- combined herbal
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)GYS1 (Glycogen synthase 1)INSR (Insulin receptor)LDLR (Low-density lipoprotein receptor)PCSK9 (Proprotein convertase subtilisin/kexin type 9)
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