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Combined Metabolic Activator
- Development stage
- Unknown
- Lead developer
- ScandiBio Therapeutics AB
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Combined Metabolic Activator** is ScandiBio’s original four-component metabolic formulation, also designated CMA1. It combines l-carnitine tartrate, l-serine, n-acetylcysteine, and nicotinamide riboside to support mitochondrial fatty-acid oxidation, NAD+ metabolism, and glutathione-dependent antioxidant capacity. The oral formulation has been evaluated in Phase 2 studies in Alzheimer's disease, Parkinson's disease, non-alcoholic fatty liver disease, and COVID-19. ([scandibio.com](https://scandibio.com/phase-2-human-clinical-trial-shows-that-metabolic-activators-improve-cognitive-function-in-alzheimers-disease-patients/))
- Other names
- CMACMCSCombined Metabolic ActivatorsCombined Metabolic Cofactor Supplementation
02
Targets
NAD (Nicotinamide adenine dinucleotide)GSH (Glutathione)
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