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Combined nerve blocks-Hillel Yaffe Medical Center-postoperative pain
- Development stage
- Unknown
- Lead developer
- Hillel Yaffe Medical Center
- Modality
- Small Molecules
- Administration
- Perineural
01
Overview
Combined nerve blocks-Hillel Yaffe Medical Center-postoperative pain refers to a regional anesthetic intervention protocol developed and studied at Hillel Yaffe Medical Center for managing pain following total knee arthroplasty (TKA). This procedural approach involves the ultrasound-guided administration of a single-shot perineural injection of 0.5% bupivacaine to target four distinct nerves: the femoral, sciatic, obturator, and lateral femoral cutaneous nerves. By providing a more comprehensive blockade of the multiple nerve pathways that innervate the knee joint, this technique is designed to offer superior postoperative analgesia compared to a standard single femoral nerve block, potentially reducing the requirement for systemic opioids such as morphine in the immediate recovery period.
- Other names
- Combined nerve blocks (femoral, sciatic, obturator, and lateral femoral cutaneous)Combined nerve blocks for TKA painCombined nerve blocks (Hillel Yaffe Medical Center)
02
Targets
NaV (Voltage-gated sodium channels)
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