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Combizym + bifidobacterium
- Development stage
- Unknown
- Lead developer
- Nordmark Pharma
- Modality
- Small Molecules, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Recombinant Proteins and Enzymes, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Combizym + bifidobacterium is a combination product consisting of digestive enzymes (as found in the branded product Combizym) and probiotic bacteria from the genus Bifidobacterium. Combizym contains pancreatin (lipase, protease, amylase) and additional fungal-derived enzymes (cellulase, protease, amylase from Aspergillus oryzae), used to aid digestion in cases of enzyme deficiency or digestive disorders[7]. Bifidobacterium is a probiotic microorganism that helps restore intestinal flora balance and may prevent gastrointestinal disturbances such as post-antibiotic diarrhea[4]. The combination aims to support both enzymatic digestion and gut microbiota health. Clinical studies have evaluated this combination for prevention of colon polyp recurrence and for improving dyspepsia symptoms[1][5].
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