Drug intelligence / Profile preview

compound 6b

Development stage
Unknown
Modality
Small Molecules
01

Overview

Compound 6b is a synthetic organic molecule designed to inhibit ferrous ion transport via the divalent metal transporter 1 (DMT1; SLC11A2). It acts as an inhibitor of DMT1, which is involved in iron uptake. Another distinct compound named "compound 6b" has been described as a derivative of the Neuromedin U (NmU) C-terminal heptapeptide and functions as a selective agonist of the Neuromedin U receptor type 2 (NMU2). These represent two different compounds sharing the same code name but with different mechanisms and targets. The DMT1-inhibiting compound was developed for modulating iron transport, potentially relevant in conditions related to iron metabolism. The NMU2 agonist derivative relates to neuropeptide receptor modulation. No specific developer or manufacturer information is publicly available for either variant under this name.

Other names
compound 6bcompound6bcompound-6b
02

Targets

SLC11A2 (DMT1)

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