Drug intelligence / Profile preview

compound 7g

Development stage
Preclinical
Lead developer
Schrödinger
Modality
Small Molecules
01

Overview

Compound 7g is an experimental **small-molecule amide-enriched 2-(1H)-quinazolinone derivative** reported in a 2024 medicinal chemistry study evaluating a series of analogs 7a-j as potential anticancer agents. In the cited work, compound 7g showed notable **in vitro antiproliferative and apoptotic activity against the DU-145 human prostate cancer cell line**. The study included **molecular docking to the epidermal growth factor receptor tyrosine kinase domain**, suggesting a possible EGFR-directed antineoplastic mechanism, but this remains **preclinical and inferential rather than clinically validated**. No established sponsor, commercial developer, brand name, formulation, manufacturing information, or clinical development program was identified from the provided source.

Other names
amide-enriched 2-(1H)-quinazolinone derivative 7g
02

Targets

EGFR T790M (Epidermal growth factor receptor T790M mutant)

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