Drug intelligence / Profile preview

compound betamethasone

Development stage
Unknown
Lead developer
Merck
Modality
Small Molecules
Administration
Intramuscular, Local Injection, Local Infiltration, Paravertebral Nerve Block, Intercostal Nerve Block, Serratus Anterior Plane Block, Thoracolumbar Interfascia Plane Block
01

Overview

Compound betamethasone is a pharmaceutical drug that combines two forms of the synthetic glucocorticoid betamethasone: betamethasone sodium phosphate and betamethasone dipropionate. This combination is designed to provide both rapid onset and prolonged anti-inflammatory effects. Betamethasone sodium phosphate is a soluble agent for quick absorption, while betamethasone dipropionate is a slightly soluble drug that acts as a reservoir for sustained release. It functions by binding to glucocorticoid receptors, affecting the transcription of proteins involved in the inflammatory response, thereby reducing inflammation, pain, and swelling. It is being investigated for various conditions including acute gout, pain after supraspinatus tendon repair, severe alopecia areata, frozen shoulder, vitiligo, and for postoperative pain management in several surgical procedures.

Brand names
DiprospanDibaosongCompound Betamethasone Injection
Other names
复方倍他米松
02

Targets

GR (Glucocorticoid receptor)

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