Drug intelligence / Profile preview

Compound Betamethasone Injection

Development stage
Preclinical
Lead developer
Merck
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Intramuscular, Intraarticular, Periarticular, Intralesional, Local Injection
01

Overview

Compound Betamethasone Injection, known by the brand name Debuzone (得宝松), is a pharmaceutical drug consisting of a combination of two betamethasone esters: betamethasone dipropionate and betamethasone sodium phosphate. This formulation provides both rapid and sustained anti-inflammatory, anti-rheumatic, and anti-allergic effects. As a synthetic glucocorticoid corticosteroid, it primarily functions by binding to glucocorticoid receptors, thereby modulating gene transcription to suppress the production of pro-inflammatory mediators and enhance the synthesis of anti-inflammatory proteins. It is indicated for a wide range of inflammatory conditions affecting musculoskeletal, allergic, and dermatological systems, as well as certain collagen diseases and neoplastic conditions. The drug is administered via injection, allowing for targeted or systemic therapeutic action.

Brand names
debuzone得宝松
Other names
复方倍他米松注射液
02

Targets

GR (Glucocorticoid receptor)

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