compound bismuth potassium citrate

Compound bismuth potassium citrate is a fixed-dose combination pharmaceutical product primarily used for the eradication of *Helicobacter pylori* infection and the treatment of associated gastrointestinal conditions such as duodenal ulcers. The combination typically consists of bismuth potassium citrate, tinidazole, and clarithromycin. Bismuth potassium citrate acts as a mucosal protective agent by forming a barrier over ulcer sites and exhibits direct antibacterial activity against *H. pylori*. Tinidazole is a nitroimidazole antimicrobial that causes DNA strand breakage in anaerobic bacteria, while clarithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. This combination is frequently evaluated in clinical trials alongside proton pump inhibitors (PPIs) like omeprazole to achieve high eradication rates in patients with active peptic ulcer disease.

Brand names

Lizhu Dele

Other names

复方枸橼酸铋钾