Drug intelligence / Profile preview

compound caoshi silkworm granule

Development stage
Unknown
Lead developer
Jinhua Hospital of Zhejiang University
Modality
Small Molecules
Administration
Oral
01

Overview

Compound Caoshi Silkworm Granule is a Traditional Chinese Medicine (TCM) hospital preparation developed by Jinhua Municipal Central Hospital for the treatment of chronic obstructive pulmonary disease (COPD). The formulation is primarily based on the herb *Stachys sieboldii* (known as Caoshican or Chinese artichoke), which is traditionally used in TCM to clear heat, detoxify, and resolve phlegm. It is specifically indicated for COPD patients presenting with the 'phlegm-heat obstructing the lungs' pattern. Clinical research conducted by the developer suggests that the granule improves pulmonary function parameters, such as FEV1/FVC, and reduces systemic inflammatory markers, including Tumor Necrosis Factor-alpha (TNF-α) and Interleukin-8 (IL-8). The drug is typically used during the stable phase of COPD to prevent exacerbations or during acute phases to alleviate symptoms like cough and excessive sputum.

Other names
Fufang Caoshican KeliCompound Stachys Sieboldii Granule

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