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Compound Cortex Phellodendri fluid (Fufang Huangbai Yiye) is a Traditional Chinese Medicine (TCM) topical solution primarily composed of extracts from *Cortex Phellodendri Chinensis* (Huang Bai), *Lonicerae Japonicae Flos* (Jin Yin Hua), *Scutellariae Radix* (Huang Qin), *Forsythiae Fructus* (Lian Qiao), and *Taraxaci Herba* (Pu Gong Ying). It is widely utilized in clinical practice for its anti-inflammatory, antimicrobial, and tissue-regenerative properties. The formulation is typically applied as a wet compress to treat various skin conditions, including acute herpes zoster, infected wounds, and inflammatory dermatoses. Its therapeutic effect is attributed to the modulation of pro-inflammatory cytokines and the promotion of wound healing through the synergistic action of its botanical components, particularly alkaloids like berberine.
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