Drug intelligence / Profile preview

compound cydiodine buccal tablets

Development stage
Phase 1
Lead developer
北京人福军威医药技术开发有限公司
Modality
Small Molecules
Administration
Buccal
01

Overview

Danoshu is a fixed-dose **buccal tablet** formulation of cydiodine and dyclonine hydrochloride being developed by Beijing Renfu Junwei Pharmaceutical Technology Development for **recurrent aphthous ulcer**. Cydiodine is intended to provide local antiseptic activity through release of active iodine, while dyclonine hydrochloride is a local anesthetic intended to reduce ulcer-associated oral pain. A completed Chinese Phase 1 study evaluated single- and multiple-dose safety, tolerability, and pharmacokinetics in healthy adults; the registry record specifically assessed dyclonine hydrochloride pharmacokinetics. ([pharnexcloud.com](https://www.pharnexcloud.com/data/lcsy_aeb3e324ad47168922ffe24c384b0732.html))

Other names
Compound Cydiodine Buccal TabletsDanoshu复方西地碘含片
02

Targets

SCN10A (Sodium channel protein type X alpha subunit)TRPV3 (Transient receptor potential vanilloid subtype 3)SCN5A (Sodium channel protein type 5 subunit alpha)

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