Drug intelligence / Profile preview

Compound Danshen Dropping Pills

Development stage
Phase 4
Lead developer
Tasly Pharmaceutical
Modality
Small Molecules
Administration
Oral, Sublingual
01

Overview

Compound Danshen Dropping Pills is a Chinese patent medicine formula composed of three medicinal herbs: Salvia miltiorrhiza (Danshen), Panax notoginseng (Sanqi), and Borneol. The active pharmacodynamic substances consist mainly of phenolic acids (including tanshinol, protocatechualdehyde, salvianolic acids), saponins (notoginsenoside R, ginsenosides), and borneol. Salvianolic acids U and T are the characteristic active ingredients. The medication works by promoting blood circulation, removing blood stasis, regulating vital energy, and easing pain. It has been widely used for treating cardiovascular diseases, particularly coronary heart disease, angina pectoris, and high-altitude heart disease.

Brand names
Guanxin Danshen Dropping PillsGDDP
Other names
CDDPFufang Danshen Diwan (Chinese transliteration)Compound Salvia Miltiorrhiza Dripping Pills
02

Targets

KDM4A (Lysine-specific demethylase 4A)JNK (Mitogen-activated protein kinase kinase kinase family)MET (Mesenchymal-epithelial transition factor receptor)VEGFR (VEGFR family)PIM1 (Proviral integration site for moloney murine leukemia virus kinase 1)PPARG (Peroxisome proliferator-activated receptor gamma)

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