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compound ginkgo biloba extract
- Development stage
- Unknown
- Lead developer
- Fangsheng Pharmaceutical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Compound ginkgo biloba extract is a botanical combination product, typically formulated as oral tablets, containing *Ginkgo biloba* extract and *Panax notoginseng*. Developed by Hunan Fangsheng Pharmaceutical, it is primarily investigated for the treatment of vascular dementia, particularly the "stasis blocking brain collaterals" syndrome in Traditional Chinese Medicine. The therapeutic effects are derived from active constituents such as ginkgolides, bilobalide, and flavonoids, which function as platelet-activating factor (PAF) receptor antagonists and antioxidants. These actions help to improve cerebral microcirculation, reduce blood viscosity, and provide neuroprotection against ischemic damage. Clinical development has focused on evaluating its efficacy and safety in improving cognitive function and activities of daily living in patients with vascular dementia.
- Brand names
- Fufang Yinxingye
- Other names
- Compound Ginkgo Biloba Extract Tablets复方银杏叶片Fufang Yinxingye Pian
02
Targets
PTAFR (Platelet-activating factor receptor)
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