compound glycyrrhiza oral solution

Compound glycyrrhiza oral solution (CGOS), also known as Brown Mixture, is a traditional combination pharmaceutical product primarily used as an antitussive and expectorant. Its standard formulation typically includes glycyrrhiza fluid extract, camphorated opium tincture, ethanol, and glycerol. The glycyrrhiza component provides anti-inflammatory and expectorant properties, while the opium tincture acts on the central nervous system to suppress cough. Recent pharmacological research has highlighted its potential therapeutic role in chronic obstructive pulmonary disease (COPD), where it appears to alleviate oxidative stress and pulmonary inflammation by inhibiting the SRC/MAPK signaling pathway. It is widely manufactured and marketed in China for the relief of respiratory symptoms associated with infections and chronic bronchitis.

Brand names

Brown Mixture

Other names

Compound Licorice Oral SolutionCGOSFufang Gancao Koufu Rongye