Drug intelligence / Profile preview

compound glycyrrhizin

Development stage
Unknown
Lead developer
Minophagen Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Meineng is a brand name for compound glycyrrhizin, a combination drug containing glycyrrhizin (glycyrrhizic acid), glycine, and DL-methionine. It is primarily used for the treatment of chronic liver disease to improve liver function and for various inflammatory skin conditions such as eczema, dermatitis, and alopecia areata. Glycyrrhizin, the active component derived from licorice root, possesses anti-inflammatory, anti-allergic, and hepatoprotective properties. Glycine and methionine are included to mitigate potential side effects of glycyrrhizin, such as pseudoaldosteronism (sodium retention and potassium loss). It is widely used in East Asia, particularly China and Japan.

Brand names
Meineng
Other names
Compound Glycyrrhizin TabletsGlycyrrhizin + Glycine + DL-Methionine
02

Targets

HSD11B2 (11β-HSD2)Cx-GJC (Connexin-based gap junction channel)HSD11B1 (11-beta-hydroxysteroid dehydrogenase type 1)HMGB1 (High mobility group protein B1)

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