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Drug intelligence / Profile preview
Compound Huangkui Granules
- Development stage
- Phase 3
- Lead developer
- Shandong Institute of Pharmaceutical Industry
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Compound Huangkui Granules is a Traditional Chinese Medicine (TCM) formulation developed by the Shandong Institute of Biological Medicine for the treatment of chronic non-bacterial prostatitis (CNP). The primary active component is derived from *Abelmoschus manihot* (L.) Medic, which contains a variety of flavonoids such as myricetin, quercetin, and hyperoside. The drug exerts its therapeutic effects through multi-target anti-inflammatory and analgesic mechanisms, specifically by inhibiting the production of pro-inflammatory cytokines like TNF-α, IL-1β, and IL-6, and by suppressing the expression of COX-2. These actions help to alleviate pelvic pain and urinary symptoms associated with chronic prostatic inflammation. It is typically administered orally in a granule dosage form.
- Other names
- Fufang Huangkui KeliCompound Abelmoschus Manihot Granules
02
Targets
IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
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